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CASE REPORT
Year : 2016  |  Volume : 36  |  Issue : 2  |  Page : 78-80

An unusual case of primary prostatic extragastrointestinal stromal tumor


1 Department of Internal Medicine, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan
2 Department of Pathology, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan
3 Department of Surgery, Division of Urological Surgery, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan
4 Department of Internal Medicine, Division of Haematology and Oncology, Tri-Service General Hospital, National Defence Medical Centre, Taipei, Taiwan

Correspondence Address:
Ching-Liang Ho
Department of Internal Medicine, Division of Haematology and Oncology, Tri-Service General Hospital, National Defence Medical Centre, Taipei
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/1011-4564.181524

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Extragastrointestinal stromal tumors (EGISTs) originate from several anatomic sites, except the digestive system. We describe an early prostatic EGIST case with lower urinary tract symptoms and a palpable lesion on digital examination. The patient received transrectal ultrasonography-guided biopsy of the prostate, and the pathological finding demonstrated positive staining for DOG-1 and CD117. Treatment included only imatinib, which shrank the tumor and led to complete remission. Because of enlarged prostate volume with tumor progression, the initial common manifestations are lower urinary tract symptoms. Surgical resection is the recommended management, particularly in bulky lesions. However, imatinib still plays an important role in long-term therapy. We also review the associated reported cases of prostatic EGISTs.


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