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CASE REPORT
Year : 2020  |  Volume : 40  |  Issue : 1  |  Page : 42-45

Paraneoplastic leukemoid reaction associated with poor prognosis in oral squamous cell carcinoma: A case report and literature review


1 Department of Radiation Oncology, Chi Mei Medical Center, Liouying, Taiwan
2 Department of Hematology Oncology, Chi Mei Medical Center, Liouying, Taiwan
3 Department of Diagnostic Radiology, Chi Mei Medical Center, Liouying, Taiwan
4 Department of Radiation Oncology, Chi Mei Medical Center, Liouying; Graduate Institute of Medical Science, Chang Jung Christian University, Tainan, Taiwan

Correspondence Address:
Dr. Sheng-Yow Ho
Department of Radiation Oncology, Chi Mei Medical Center, Liouying, 201, Taikang, Liouying, Tainan 73657
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jmedsci.jmedsci_86_19

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Paraneoplastic leukemoid reaction (PLR) is exceedingly uncommon syndrome in oral cancer and has implicated a worse outcome. This report describes a case of buccal mucosa cancer encountered PLR syndrome during the course of tumor progression. We conduct a literature review to highlight the relationship between PLR and the outcome in oral cancer. PLR is associated with rapid tumor growth and worse outcome in head-and-neck cancer.


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