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CASE REPORT
Year : 2020  |  Volume : 40  |  Issue : 3  |  Page : 137-140

Intracranial germ cell tumor metastasis to the peritoneal cavity through the ventriculoperitoneal shunt


1 Department of Internal Medicine, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan
2 Department of Pathology, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan
3 Department of Internal Medicine, Division of Gastroenterology, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan

Correspondence Address:
Dr. Yu-Lueng Shih
Department of Internal Medicine, Division of Gastroenterology, National Defense Medical Center, Tri-Service General Hospital, No. 25, Section 2, Cheng-Gong Road, Neihu 114, Taipei
Taiwan
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jmedsci.jmedsci_25_20

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Intracranial germ cell tumors (GCTs) are uncommon and may cause obstructive hydrocephalus, making adequate drainage necessary in symptomatic patients. Here, we present the case of a 36-year-old male patient with intracranial germinoma metastasis to the peritoneal cavity. He had a medical history of pineal germinoma status post ventriculoperitoneal (VP) shunt implantation and definitive radiotherapy. Two years later, the patient presented with epigastric pain, and intra-abdominal metastasis through the VP shunt with malignant transformation to a nongerminomatous GCT was noted. Chemotherapy followed by surgical resection was arranged, and he got disease free after treatment. The present report alerts clinicians to the progression of this uncommon disease and suggests that a thorough physical examination is imperative in patients with a history of intracranial GCTs who have undergone VP shunt implantation, and an alternative therapeutic plan should be considered to treat intracranial GCT-related obstructive hydrocephalus.


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