Head and Neck Lymphomas: Review of 151 Cases
Chao-Yin Kuo1, Cheng-Ping Shih1, Li-Hsiang Cheng1, Shao-Cheng Liu1, Feng-Hsiang Chiu1, Yuan-Yung Lin1, Je-Ming Hu2, Yueng-Hsiang Chu1
1 Department of Otolaryngology-Head and Neck Surgery, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan, Republic of China
2 Department of Surgery, Division of Colorectal Surgery, Tri-Service General Hospital, National Defense Medical Center; National Defense Medical Center, Graduate Institute of Medical Sciences; National Defense Medical Center, School of Medicine, Taipei, Taiwan, Republic of China
Department of Otolaryngology-Head and Neck Surgery, National Defense Medical Center, Tri-Service General Hospital, Taipei, Taiwan, Republic of China
Department of Otolaryngology–Head and Neck Surgery, National Defense Medical Center, Tri-Service General Hospital, 325, Section 2, Cheng-Kung Road, Taipei 11490
Source of Support: None, Conflict of Interest: None
Aim: Treatment of lymphoma differs from head and neck carcinomas. The aim of this study was to provide a comprehensive of review lymphomas arising in head and neck region. Methods: Patients between 2003 and 2015 with lymphomas in head and neck region were retrospectively reviewed with pathology subtype, age, gender, location, and diagnostic procedure. Results: One hundred and fifty-one lymphoma patients were enrolled. Diffuse large B-cell lymphoma accounted for 56.3% of all patients, followed by follicular lymphoma (6.0%) and NK/T-cell lymphoma (6.0%). Nearly 38.4% of patients manifested as enlarged cervical node while another 61.6% presented as extranodal lymphoma with tonsils (21.8%) the most commonly affected site, followed by parotid gland and tongue base. Open surgery or excisional biopsy had the highest sensitivity of 95.8% for a confirmed diagnosis, followed by punch biopsy (74.7%), core biopsy (51.0%), and fine-needle aspiration (2.2%). Conclusions: Lymphoma is frequently encountered in head and neck region. Early diagnosis was made possible by detailed examinations and adequate diagnostic procedure with consideration of both procedure sensitivity and risks.