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Figure 4: Pathology of the arterial atherosclerotic lesion. (a) H and E staining. Original magnification, each, ×400; (b) N/M ratio. Antroquinonol (Antroq)treated carotid artery ligation (CAL) mice showed significantly reduced N/M ratios compared to those of corn oiltreated (disease control), from 200 to 900 μm away from the site of ligation. The horizontal dashed line indicates the mean of levels from normal control mice. CAL, carotid artery ligation model; N/M ratio, ratio of neointima to media area. The data are the mean ± SE for eight mice per group. **P < 0.001, ***P < 0.005. n = 10 mice per group. Prediction of N/M ratio with the CAL (X1) and Antroqtreated CAL mice (X2) using regression model to fit the explanatory formulas of Y = β0 + β1X1 + β2X2, intercept = 4.403, β1: −0.213, β2: −2.257, R^{2} = 0.924 
