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Figure 2. Valproic acid (VPA) treatment exhibits an anti-oral cancer cell effect. Oral cancer cells (squamous cell carcinoma [SCC] 25 and OECM-1) were treated with VPA for 72 h with indicated concentrations. The viability of these two cell lines was assessed by MTT assay. The results indicated that 2 mM VPA induced (a) SCC 25 and (b) OECM-1 cell deaths (n = 3; *P < 0.05; **P < 0.01; ***P < 0.001) |
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