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  Indian J Med Microbiol
 

Figure 1: Effects of istradefylline on (a) core temperature, (b) heart rate, (c) mean arterial pressure, and (d) pressor response to norepinephrine in heatstroke rats. Depicted are the changes of core temperature and hemodynamics in animals that received vehicle (control, n = 6), received istradefylline (control + istradefylline, n = 4), heatstroke plus vehicle (heatstroke, n = 6), and heatstroke plus istradefylline (heatstroke + istradefylline, n = 7). Data are expressed as mean ± standard error of mean * P < 0.05, all versus control;#P < 0.05, with versus without istradefylline in heatstroke rats

Figure 1: Effects of istradefylline on (a) core temperature, (b) heart rate, (c) mean arterial pressure, and (d) pressor response to norepinephrine in heatstroke rats. Depicted are the changes of core temperature and hemodynamics in animals that received vehicle (control, <i>n</i> = 6), received istradefylline (control + istradefylline, <i>n</i> = 4), heatstroke plus vehicle (heatstroke, <i>n</i> = 6), and heatstroke plus istradefylline (heatstroke + istradefylline, <i>n</i> = 7). Data are expressed as mean ± standard error of mean * <i>P</i> < 0.05, all versus control;<sup>#</sup><i>P</i> < 0.05, with versus without istradefylline in heatstroke rats