Sympathovagal imbalance in prehypertension status

Yi-Jhih Huang; Tsai-Wang Huang; Hung Chang; Wen-Hui Fang; Tung-Wei Kao; Wei-Liang Chen; Ying-Jen Chen; Yung-Lung Chang; Li-Wei Wu

doi:10.4103/1011-4564.185214

Users Online: 4224

ORIGINAL ARTICLE

Year : 2016 | Volume : 36 | Issue : 3 | Page : 113-119

Sympathovagal imbalance in prehypertension status

Yi-Jhih Huang¹, Tsai-Wang Huang¹, Hung Chang¹, Wen-Hui Fang², Tung-Wei Kao³, Wei-Liang Chen⁴, Ying-Jen Chen⁵, Yung-Lung Chang⁶, Li-Wei Wu⁴
¹ Department of Surgery, Division of Thoracic Surgery, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
² Department of Family and Community Medicine, Division of Family Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
³ Department of Family and Community Medicine, Division of Family Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center; Department of Family and Community Medicine, Division of Geriatric Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
⁴ Department of Family and Community Medicine, Division of Family Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center; Department of Family and Community Medicine, Division of Geriatric Medicine, School of Medicine, Tri-Service General Hospital, National Defense Medical Center; National Defense Medical Center, Graduate Institute of Medical Sciences, Taipei, Taiwan, Republic of China
⁵ National Defense Medical Center, Graduate Institute of Medical Sciences, Taipei, Taiwan, Republic of China
⁶ Department and Graduate Institute of Biochemistry, National Defense Medical Center, Taipei, Taiwan, Republic of China

Correspondence Address:
Dr. Li-Wei Wu
Tri-Service General Hospital, National Defense Medical Center, 2F, 325, Sec 2, Cheng-Gong Road, Neihu District, Taipei City 114, Taiwan
Republic of China

Source of Support: None, Conflict of Interest: None

Check

DOI: 10.4103/1011-4564.185214

Background: Heart rate variability (HRV) had been promoted for longer than half a century to monitor the activity of autonomic nerve systems. Previous studies have not clarified the relationship between HRV and prehypertension (pre-HTN) status compared with the normal group. We aimed to figure out the optimal model or cutoff point for predicting the possible pre-HTN status. Patients and Methods: We retrospectively collected and reviewed 2586 Asian people who had joined annual physical examination in Tri-Service General Hospital at 2013. The patient profiles such as age, gender, body height, body weight, body weight index, waist circumferences, and serological biochemistry data were analyzed and correlated with HRV parameter. Results: A total number of 909 patients were enrolled in our study. The physical stress index (PSI) owed a small but most significant Spearman's relation coefficient (r = 0.118, P< 0.001) among the other HRV parameters. Statistical significant parameters exist between the normal blood pressure group and pre-HTN group other than gender factor. The measured blood pressure increased with elevated PSI level. A PSI level ≥58.4 has a significant β coefficient in each linear regression model for systolic blood pressure and diastolic blood pressure with a P< 0.001 for trend. Conclusion: The PSI level gains a positive correlation to elevated blood pressure. Our study emphasized that PSI is an efficient HRV parameter which represents higher risks for pre-HTN status and elevated blood pressure while the PSI level is >58.4. Early intervention to these participants may decrease cardiovascular events in the coming future.

[FULL TEXT] [PDF]*

Table of Contents

Similar in PUBMED

Search Pubmed for

Search in Google Scholar for

Related articles

Citation Manager

Access Statistics

Reader Comments

Email Alert *

Add to My List *

* Requires registration (Free)

Article Access Statistics

Viewed	3522

Printed	126

Emailed	0

PDF Downloaded	218

Comments	[Add]