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LETTER TO EDITOR
Year : 2020  |  Volume : 40  |  Issue : 6  |  Page : 298

Afebrile Wuhan Coronavirus Infection and Expected False Negative of Thermoscanning for Screening of Immigrant


1 25 Medical Center, Bangkok, Thailand
2 Department of Community Medicine, Dr. D Y Patil University, Pune, Maharashtra, India; Department of Tropical Medicine, Hainan Medical University, Haikou, China

Date of Submission04-Feb-2020
Date of Decision06-Feb-2020
Date of Acceptance14-Feb-2020
Date of Web Publication05-Apr-2020

Correspondence Address:
Dr. Rujittika Mungmunpuntipantip
26 Medical Center, Bangkok
Thailand
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jmedsci.jmedsci_21_20

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How to cite this article:
Mungmunpuntipantip R, Wiwanitkit V. Afebrile Wuhan Coronavirus Infection and Expected False Negative of Thermoscanning for Screening of Immigrant. J Med Sci 2020;40:298

How to cite this URL:
Mungmunpuntipantip R, Wiwanitkit V. Afebrile Wuhan Coronavirus Infection and Expected False Negative of Thermoscanning for Screening of Immigrant. J Med Sci [serial online] 2020 [cited 2020 Nov 24];40:298. Available from: https://www.jmedscindmc.com/text.asp?2020/40/6/298/281983



Dear Editor,

Wuhan coronavirus infection is a new emerging disease that becomes a global problem. After its first emergence in China in December 2019, it spread to several countries in the early 2020.[1],[2] The continuous spread in the imported countries is reported.[3] At present, the important preventive measure against this new disease in countries that there is still no disease is the use of immigrant screening. The basic tool is thermoscanning. However, thermoscanning focuses on fever detection. The false negative due to afebrile infection is possible.

Here, the authors reappraised on the available data on patients with Wuhan coronavirus infection[4] to estimate the expected rate of the afebrile infected case. Based on the available data on 99 cases, the fever is seen in 82 cases,[4] the estimated afebrile infection rate is equal to 17.17% (95% confidence interval = 11.14%–26.47%). Therefore, there is high rate of false-negative results from thermoscanning for the screening of immigrants. This can result in possible further spread in new countries and the chain of continuous spread to the third country in possible. In fact, there is already a case of novel infection detected in Korea in a patient without a history of travel to China but with a history of travel to Thailand, where the disease is already imported from China.

In conclusion, the use of thermoscanning for the screening of immigrant might not sufficient for effective prevention of imported Wuhan coronavirus infection.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Hsia W. Emerging new coronavirus infection in Wuhan, China: Situation in early 2020. Case Study Case Rep 2020;10:8-9.  Back to cited text no. 1
    
2.
Yasri S, Wiwanitkit V. Editorial: Wuhan coronavirus outbreak and imported case. Adv Trop Med Pub Health Int 2020;10:1-2.  Back to cited text no. 2
    
3.
Sookaromdee P, Wiwanitkit V. Imported cases of 2019-Novel Coronavirus (2019-nCoV) Infections in Thailand: Mathematical modelling of the outbreak. Asian Pac J Trop Med. Available from: http://www.apjtm.org/preprintarticle.asp?id=277516. [Last cited on 2020 Feb 04].  Back to cited text no. 3
    
4.
Chen N, Zhou M, Dong X, Qu J, Gong F, Han Y, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: A descriptive study. Lancet 2020;[Epub ahead of print].  Back to cited text no. 4
    




 

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